Name: Abhijit Chowdhury
Designation: Professor and Head, Dept. of Hepatology, IPGME&R and SSKM Hospital,
Secretary and Adjunct Professor, BioMedical Genomics Centre, Kolkata
Highest Educational Qualification: MD, DM, FNASc
 

 

Research

Molecular epidemiology of Hepatitis viruses
liver disease burden in the community
Nonalcoholic Fatty Liver Disease – Metagenomics and Genetics

 

Ongoing Project

Genomic and Epigenomic analyses of Non Alcoholic Fatty Liver Disease (NAFLD) in the Indian population

 

Project Co-ordinators

Prof Abhijit Chowdhury                                   PI

Dr. Priyadarshi Basu                                       Co-PI

Dr. Analabha Basu                                          Co-I

Ankita Chatterjee                                           Research Scholar

 

In this project we are undertaking genome-wide association analyses of NAFLD, which will complement our understanding of this novel Indian trait, which is quite distinct from the Western phenotype, which is associated with obesity. Epidemiologic evidence indicates that NAFLD in lean individuals might be a consequence of the transitional nutritional features or malnutrition in these individuals. We think that these factors might have a huge influence on the methylome of these individuals. Therefore, a second objective of my laboratory is to examine the roles that epigenetic factors play in NAFLD susceptibility and whether there is any interaction with genetic factors.

 

Selected Publications

 

Ghosh A, Ghosh A, Datta S, Dasgupta D, Das S, Ray S, Gupta S, Datta S, Chowdhury A, Chatterjee R, Kant Mohapatra S, Banerjee S. (2016) Hepatic miR-126 is a Potential Plasma Biomarker for Detection of Hepatitis B Virus Infected Hepatocellular Carcinoma. Int J Cancer. doi 10.1002/ijc.29999. [Epub ahead of print]

 

Aithal GP, Das K, Chowdhury A. (2014) Epidemiology of Nonalcoholic Fatty Liver Disease (NAFLD), in GI Epidemiology Diseases and Clinical Methodology, Second Edition (eds N. J. Talley, G. R. Locke, P. Moayyedi, J. West, A. C. Ford and Y. A. Saito), John Wiley & Sons, Ltd, Chichester, UK. doi 10.1002/9781118727072.ch32.

 

Ghosh TS, Gupta SS, Bhattacharya T, Yadav D, Barik A, Chowdhury A, Das B, Mande SS, Nair GB. (2014) Gut microbiomes of Indian children of varying nutritional status. PLoS One. 9(4)e95547.

 

Das K, Chowdhury A. (2013) Lean NASH distinctiveness and clinical implication. Hepatology International. 7(2)806-813.

 

Das K, Das K, Mukherjee PS, Ghosh A, Ghosh S, Mridha AR, Dhibar T, Bhattacharya B, Bhattacharya D, Manna B, Dhali GK, Santra A, Chowdhury A. (2010) Nonobese population in a developing country has a high prevalence of nonalcoholic fatty liver and significant liver disease. Hepatology. 51(5)1593-602.